This is a universal human physical experience, which I suppose represents unintentional bodily clinging and in the Buddhist scheme of things, the simple pain of inhabiting a body. For this natural discomfort we employ skillful means to correct the condition: exercise, eating more fiber, changes of routine.
It's probably stretching the metaphor, but melancholy also afflicts us when there is insufficient elimination of foul and festering mental formations like greed, hatred, fear, aversion, anger and so on. This is the dukkha that results from clinging. The Buddha offered us medicine to reduce and eliminate the clinging that creates dukkha.
Aside from meditating because we might want to calm the mind, in accordance with the Buddha's prescription, we practice clear seeing to diagnose where we are holding. What are the objects of our attachment? Often, just that awareness provides the condition necessary for some, or complete, relinquishment to take place.
Posted by Deb.